Platform Trials

31
Mar
6 min read

The Grammar No One Reads: How Platform Trials Standardize Statistical Design

If you look at a single ComboMATCH substudy on ClinicalTrials.gov, you see a clinical trial. Two-stage design, 30 patients, objective response rate. It looks like any Phase II study. If you look across substudies, you see something different. You see a system. I was a statistician on two SWOG

26
Nov
4 min read

When Every Company Becomes a Trialist

In 2014, during a major snowstorm, Uber ran a randomized test by turning off surge pricing for a subset of riders. Some waited longer. Others never got a ride at all. It wasn’t just a pricing tweak. It was a trial of behavior, supply, and equity. Trials, once reserved