Data Quality

09
Dec
3 min read

The Surrogate Trap: When the Mechanism Works But the Patient Dies

In the late 1980s, cardiologists thought they had cracked the code. They knew that patients who developed irregular heartbeats, premature ventricular contractions (PVCs), after a heart attack were more likely to die. They had drugs, encainide and flecainide, that reliably suppressed those irregular beats. The intuition was flawless: Suppress the

03
Dec
5 min read

What A/B Testing Teams Can Learn from 40 Years of Oncology Trial Mistakes

What oncology learned the hard way—and tech keeps relearning.