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29
Jan
4 min read

I Asked an LLM to Design My Clinical Trial

I asked an LLM a question that junior biostatisticians ask senior biostatisticians all the time: Should I use a Bayesian borrowing design for my Phase 2 single-arm oncology trial? Here's what I got back. The LLM Response Should I use a Bayesian borrowing design for my Phase 2

27
Jan
7 min read

Qalsody: The Probability of Harm

What FDA Actually Decided When the Trial Failed

22
Jan
3 min read

Calibrated Bayes: The Framework You’re Already Using

If you’ve ever justified a Bayesian design to a regulator, you’ve already been practicing calibrated Bayes, even if you never called it that.